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N-Bombs / Smiles

25-I-NBOMe blotter 

A new pair of phenethylamine research chems have been making waves lately since their appearance in 2010 through research chemical distributors. Known casually as "N-Bombs" or "Smiles" and technically as 25-I-NBOMe / 25-C-NBOMe (or 2C-I-NBOMe / 2C-C-NBOMe respectively), these 2C-I and 2C-C relatives are potent psychedelics which are active in the microgram dose range (under 1mg). This dose range is more traditionally considered "the realm of LSD" as far as hallucinogens and psychedelics go, and with a timeline and effects set that is considered comparable in ways to LSD it's no surprise that certain areas and communities have encountered dealers presenting these unpronounceable new chemicals simply as "new acid", "synthetic mescaline", as well as the somewhat more clear "Smiles." 

The photo above shows blotter paper carrying 25-I-NBOMe, ordered in this form over the internet and obviously in a form that could be confused with LSD blotter. (Of course, DOI/DOB have also been sold on blotter as fake acid for some time now.)

Here's some background information: 25-I is generally described as more visual than 25-C and sometimes more difficult to handle, psychologically and physically. These drugs are active at less than half a miligram and often overwhelming at 1mg+. (dose especially strong intranasally, which is the route of administration that has been most linked to hospitalizations and lethal overdoses). Somewhat bitter. Definitely psychedelic in effects, can pass as acid to the inexperienced.

Fairly easy to obtain and quite cheap. Presents serious risk due to improper dosing (some users report that the same dose on the same person can have widely varying degrees of effects at different times), availability has caused many people to attempt laying blotter who probably shouldn't and miscalculate the dosage of each.

Although a fair number of people have had safe and enjoyable experiences with these chemicals, hospitalizations and deaths have been reported .  It is definitely possible to have a lethal overdose situation, at least in the case of 25-I-NBOMe, and at present there is no information available as to what the LD50 "standard toxic dosage" is for a human being.

Timeline of effects is fairly close to that of LSD, a definite advantage over the DO* series.

These psychedelic stimulants are classified as phenethylamines, and not amphetamines, therefore not subject to the Canadian Controlled Drugs & Substances Acts clause regarding analogues of amphetamine. 25-I-NBOMe is more popular and widespread than 25-C-NBOMe, hence the perceived greater danger may simply be due to more cases of the first having been tried out at all.

These chemicals are not particularly active orally and have mainly been consumed sublingually (under the tongue or against the gums), which is also the reason people have attempted intranasal ingestion which is seemingly unusual for what they may have been sold as an "LSD-like" drug. When complexed with the sugar HPbCD (hydroxy propyl beta cyclodextrin), N-Bombs can gain some oral bioavailability and greater sublingual bioavailability. (How much more is the subject of debate).

More images of 25-I-NBOMe and 2C-I-NBOMe as powder, blotter, and in other forms are available on Erowid, with new ones appearing regularly. (The drugs have also been distributed diluted into liquid.) As with any research chems, tread especially carefully if you encounter or suspect you have encountered these drugs and are considering consuming them. As previously stated, the effects can be unpredictable even when a user consumes the same amount of the same batch that they previously had, and the only real research having been done on these drugs has been "in-the-wild" user reports.

If you have any information pertaining to these drugs, especially related to Canada, feel free to contact us via or or :)

Synthetic Cannabinoid FAQ: So Do I Smoke It?

"Spice" containing JWH-018 


By Eric Oulster


The news has exploded recently about stuff being sold that is supposedly similar to pot. For the sake of this FAQ, we’ll refer to them as ‘Synthetic Smokables’. There is little research on these substances, even by professional drug researchers and lawmakers. As a result, it can be kind of hard to find information about these drugs right now. Whether you want to try them or stay clear, that’s your own decision, but maybe we can help answer some questions you might have about them.

So what is this stuff?
Well, at its most basic, these are smokable substances sold in convenience stores and head-shops. Sometimes they are called ‘spices’, but are sold under many other names, too. They are often marketed as being something unlike a drug, such as an “incense” or “potpourri”. Despite these names, they are still sold to smoke. Synthetic Smokables often come in a professional looking package, made of plastic and with a brand name. They usually range in prices from 5-15 dollars, and some places give out samples.

Is it a chem or a herb?

Most of these drugs are chemicals that are manufactured in a laboratory setting (most likely in Asia), then shipped to Canada and the U.S. Sometimes after this, the chemicals are mixed into a material that looks like dried plant matter so that it is easier to smoke and looks more ‘earthy’. Sometimes they are sold as oils. Other times, they are sold in a powdery form. Regardless, these drugs are manufactured chemicals.

How would I do these?
So far, the two routes of administration discussed regarding these drugs are in a smokable form, and on rare occasion, in an oral form.  It is advisable to consult your source on if it is a smokable or oral version, because smoking the oral form could cause an overdose and doing an oral dose of the smoking form might not affect you.

What’s in these drugs?
There are a variety of different drugs that go into these smokables, most of them being sold fall under the category of Naphthoylindoles.

What the flying f*** is a Naphtho-whatever?
You may know some of these chemicals as being under the ‘JWH’ family. Jwh-018 and Jwh-073 are in this family. Beyond that, we don’t really have a ‘street name’ for them yet. In terms of brain chemicals, they focus on the CB1 and CB2 receptors, which are also used by cannabis. This may explain why many people say the drugs feel similar to pot.

So are they legal?
Yes and no...These drugs fall into a legal grey area. You are allowed to sell the substance for research purposes if you have the proper paperwork. For human consumption, things start to get a little sketchy.
The wholesale suppliers are likely getting them 100% legally, while the people who are selling them as smokable products are probably working on loopholes. However, any substance that is supposedly “like cannabis” is supposed to be illegal for sale.
As for personal possession, we can’t say for certain if any charges could be laid - but it is important to note that most of these are still above the counter substances - even if they are only quasi-legal.

Are they going to be illegal?
There seems to be a game of cat and mouse going on between lawmakers and chemists with these substances. Once lawmakers ban a specific set of substances, chemists synthesize a similar set of chemicals that aren’t illegal and start selling them in these synthetic smokables. Chemists usually know more about chemistry than lawmakers, so as a result the chemicals in these drugs shift slightly and the product as a whole stays legal.
Another sneaky tactic some synthetic smokable dealers do is to not disclose their active ingredients on the package. It becomes really hard for lawmakers to ban a chemical or to enforce its ban when they don’t even know what it is.

Aren’t they legally obliged to say what is in their drugs?
Since a lot of these products state on the packaging “Not for human consumption”, they get away with it. Unfortunately for the user, this often means you can’t be entirely sure what is in them.

What about in the US?
The United States also seems to be playing a game of cat and mouse with chemists, but the lawmakers over there seem to be a couple steps ahead of the ones in Canada. The best advice we can give is to not bring synthetic smokables over the border! For those wishing to use in America, there are likely to be some available in the States, but they are also likely to be different from the ones available here in Canada. The same goes vice-versa: don’t bring American Synthetic Smokables into Canada.

So are these Synthetic Smokables bad for you?
There is still a lot of research going into these substances, so we can’t say for certain how neurotoxic they are. There has been one overdose resulting in death confirmed on JWH-018, and there have been reports of non-fatal overdoses occurring on Synthetic Smokables confirmed as well.

It’s important to note that this ISN’T pot though. Since these chemicals haven’t been as thoroughly researched we don’t know what kind of brain or organ damage could possibly result from regular use. We strongly recommend not trying the “smoke err’y day” route that many pot smokers choose to do with Synthetic Smokables. Play it safe and don’t go too hard.
Multiple trip reports have stated that regular use results in a decreased appetite, with multiple daily uses resulting in eating as little as one or no meals a day. If you intend to or are using this frequently, make sure you are eating well!

We also don’t have too much knowledge on the addictive potential of these drugs. Just like all other drugs, however, it is important to be aware of how much, and how often, you are using.

Can I take this stuff with any other drugs?
We have very little knowledge of mixing Synthetic Smokables with other substances. At the moment, our advice is to remember that this isn’t pot and even though it works on similar receptors in the brain, mixing it with other drugs can result in drastically different, and potentially dangerous, effects when compared to mixing pot with other drugs.
Stay Safe! Though we highly recommend not mixing Synthetic Smokables, we will suggest that if you do to at least use low dosages of both substances in order to avoid more dangerous situations that can result from a bad drug combination.

I have a question related to Synthetic Smokables that isn’t covered on this FAQ.
You can always contact the Trip!wire at (647) 822-6435 for individual questions. You can also approach your friendly neighbourhood Trip! members at our next outreach event, or reach us through Facebook at

I have information about Synthetic Smokables that I feel is important to share with you.
We’d love any additional information you have on this topic!
E-mail us at

Bad Trips Survey

Short online survey (10 questions) about a bad trip you've had!

Tell us about your bad trips, how you dealt & what you learned so we can help others!

Share with friends so we can get more data! 

Restorative Justice & Bill C-10

A couple of weeks ago (November 18-25) was Restorative Justice Week in Canada. This is a week Correctional Services Canada and the Canadian Government has selected to recognize the importance of and promote Restorative Justice in Canada. Restorative Justice can be defined as: finding peaceful and collaborative ways of addressing crime and resolving conflict in our society while promoting recognition of harm, voluntary participation, inclusion, safety, and facilitated dialogue. The idea of restorative justice (as it relates to the criminal justice system) is to provide a way for offenders to make amends for their crime in an effort to help them further understand the full impact and scope of how their actions have affected others in their community. The other, more common option in dealing with crime is to incarcerate the offender for a set period of time based on the seriousness of the offense at the expense of taxpayers, and quite often also to the detriment of the offender.

Restorative Justice week, which this year has the theme attached to it of ‘Diverse Needs; Unique Responses,’ comes at a time when we are in the midst of a crucial turning point in the future of the Canadian Justice System. Bill C-10, otherwise known as the Safe Streets and Communities Act was passed in March of 2012, and recently the laws targeting ‘serious’ drug crimes came into effect (on November 6, 2012). While the full scope of Bill C-10 refers to unrelated issues other than just drug crimes (such as increasing penalties for sexual offenses against children), the implications of this Bill are sure to change the face of what criminal justice looks like in Canada. Numerous aspects of this bill have been the source

Monopoly jail of much controversy since being introduced. There are many accounts during the debate of this bill of expert witnesses being cut-off from speaking mid-sentence after being given only 5 or so minutes to speak about the extremely complicated, multi-faceted issues that this bill attempts to address.  There have also been allegations of the bill not properly being inspected or researched, with certain parts of it having previously been studied and amended to fit the findings of the research, only to have these changes taken out and the bill being passed in its original, unrealistic and uncompromising state.

When holding the implications of Bill C-10 up against the spirit of Restorative Justice week, many contradictions quickly come to light. First off, the passing of the laws contained in C-10 guarantee that more Canadians (many of them youth) will be put in jail for longer terms, often for less serious (non-violent) crimes. It removes much of the leeway that judges have in using their own judgment when dealing with certain offenses by imposing mandatory minimum sentences, as well as bringing into effect harsher sentencing principles and increasing wait times before individuals can apply for pardons. These are just a few of the many implications the passing of this bills holds, all of which are directly opposed to the spirit and idea of restorative justice in Canada. The concept of restorative justice is based on the idea that the punishment for an offense should in some way relate to the crime, and if possible, should give the offender the chance to make right what they have done wrong. The nature of Bill C-10 denies this foundational principle. C-10 does not seek to rehabilitate individuals and shows very little interest in deterring crime, but instead seeks to lock more people up for longer periods of time at the expense of Canadian taxpayers. It is also important to mention that there were some changes made to the Drug Treatment Court program, and that in some ways, the changes made (for example, admitting that relapses in drug use are common and a reality of drug addiction treatment) show at least a tiny glimpse of harm-reduction attitudes seeping into legislation.

As countless studies have shown, the real way to prevent crime in any society is with prevention strategies: Outreach, education and creating opportunity for people so they are not put in a position where breaking laws and committing crimes are an attractive option. What has also been proven in many different arenas is that introducing harsher penalties and stricter sentencing guidelines does not deter anyone from breaking laws, but simply increases the number of offenders any given justice system is forced to deal with. In ignoring these simple facts, the Canadian Government is guaranteeing a bleak future for many (mainly young) Canadians who are at-risk of becoming offenders, and in the process, ignoring the very essence of what Restorative Justice Week is all about, as it fails to recognize the diverse needs of Canadian offenders while providing little or no opportunity for a unique response.

What You Should Know
Bill C-10 called for amendments to The Controlled Drugs and Substances Act, among many other things. Here's what you should know:

  • ImposedMandatory Minimums mandatory minimum penalties for ‘dealers (VERY vague & broadly defined), repeat offenders or people who are carrying both drugs and weapons’ as well as anyone involved in ‘organized crime’ (organized crime being defined as a group of three or more people who commit a crime for material gain) – these are referred to in the legislation as ‘aggravating factors’.

  • Minimum two year sentences now imposed for anyone caught committing a (drug related) offense ‘in or near a school, on or near school grounds, or in or near any other public place usually frequented by persons under the age of 18’ (this could be almost ANYWHERE. Again, very vague).

  • Minimum sentence of 6 months for growing 6 marijuana plants. The intent to distribute must be proven, but distribution includes giving a small amount to or sharing a joint with a friend. This increases to 9 months if the person is renting their residence.

  • Minimum sentence of 18 months for making cannabis oil, hashish, or edible products, such as cookies or brownies,. This puts a great number of medicinal cannabis users who use these products instead of smoking at risk.

  • MDMA, a substance used in the drug "ecstasy‟ rescheduled. This makes ecstasy, a drug used predominantly by young people, a schedule 1 drug along with heroin and cocaine (increasing the penalty for possession). This also means that anyone sharing ecstasy could face automatic jail time under Bill S-10.

  • Drug "trafficking‟ includes selling, but it also includes passing, giving and sharing. This blurry line between "dealer‟ and "user‟ quickly becomes dangerous as people now defined as "dealers‟ under Bill S-10 face automatic prison time, even for a first offence.

  • The Courts may choose not to impose a mandatory sentence, if the offender completes a Drug Treatment Court (DTC) program

-    The Drug Treatment Court Program facilitates the treatment of drug offenders by providing an intensive, court-monitored alternative to incarceration. It is said that drug treatment courts have a more humane approach to addressing minor drug crimes than incarceration – read more about the DTC Program here

  • A 2002 Canadian Department of Justice report concluded that mandatory minimum sentences (MMS) are the least effective strategy in combating drug offences, and further research has shown that a greater focus on criminal enforcement to address drug crime leads to higher levels of violence in those communities

  • Mandatory-sentencing policies have produced record incarceration rates of non-violent drug users in the United States.

The repercussions of Bill C-10 are simple; people caught and charged with possession of illegal substances are now MUCH more likely to go to jail. Even first time offenders. This creates a drain on tax dollars to lock more people up for longer periods of time, but also stops each offender from contributing to society (paying taxes, community service as well as contributing in other ways such as creating art and pursuing meaningful relationships). It is also likely that a large number of these young offenders will come out of prison having become a more jaded and hardened individual who is more likely to commit another crime. Harsher penalties also discourage ‘Mom and Pop’ type shops from continuing to offend, leaving more opportunity for organized crime to take over which can lead to more violence in competition for customers/territory.

Read the entire Bill C-10 legislation here
*Thanks to the CSSDP (Canadian Students for Sensible Drug Policy) for some of the information listed above

Educate & Protect Yourself - Know Your Rights
It is very important to know your rights, and know your options should you run into trouble with the law. Below are some links to obtaining legal information/legal counsel in Toronto:

  • The Central Toronto Community Health Centres (168 Bathurst St.): 416-703-8482 (has a youth lawyer in every Tuesday afternoon from 2:00 PM - 4:00 PM that is available on a drop-in basis for helping you sort out your legal troubles.)
  • Community Legal Education Ontario (CLEO) (provides online information and materials about legal rights in many areas i.e. youth justice, immigration, language, social assistance, employment, health)
  • Justice for Children and Youth: 1-866-999-5239 | (offers summary legal advice, information and assistance to young people, legal representation for low income youth in conflict with legal, educational, social service or mental health systems, among other things)
  • Ontario Women’s Justice Network (OWJN): (online information for women and youth on the law)
  • Downtown Legal Services: 416-934-4535 (For assistance with criminal matters among other things)

    Time does not stop crime

AIDS 2012 Conference Review

AIDS 2012 banner
Surving, Stories & Stigma
I came to Washington for AIDS 2012 hoping to learn from the many sessions as well as meet other's who have joined the global effort to end HIV/AIDS. While I was exposed to a diversity of panels and sessions from around the globe showcasing the hard work of individuals from all walks of life that have inspired me to continue to be an advocate, what touched me the most were the personal stories that I found throughout the conference. Stories of love, of life, and of birth, and of death. Stories of health and illness, and so many stories of survival. Some stories were accompanied by photographs or art , some were in movies screened in the Global Village. Others were not accompanied by any imagery. The words laid bare yet ever still so powerful.

As I stopped to read these stories and consider them each individually, a noticed a theme among them that I could not ignore. While many people living with HIV or AIDS continued to live productive lives, engaging in a number projects and working relentlessly in their communities, I was troubled by re occurring commonalities- discrimination, isolation, and stigma. As it was well put in the Thursday performance Music and Musings from the Life of a 27 year Survivor, many of the everyday social barriers that people living with HIV/AIDS face constitute “components for an extremely lonely existence”.

I could not help but wonder why it was that as we joined hands during this one week in Washington, making promises not only to ourselves, but to future generations, that loneliness from isolation due to social discrimination still pervaded the daily experiences of positive peoples. And for this reason I believe that we must continue in our efforts to develop not only more scientific advancements, but also engage the media in providing more educational messages concerning HIV/AIDS while highlighting the very really harms of stigma. We must make it up to personally each and every one of us to de-mystify and lessen the fears associated with HIV/AIDS.

By coupling scientific with social goals that promote equity, acceptance and compassion, we can foster a sense of community that has the potential to take us above and beyond. From the depth of my heart, I want to thank all of those who shared or contributed in the sharing of stories that have greatly changed my perspective.
-- Yamina Sara Chekroun (YouthRISE worker, former TRIP! Outreach Worker)  
Yamina Sara presenting TRIP! at AIDS 2012 
Yamina Sara Chekroun presenting at AIDS 2012 Conference
From the youthAIDS2012 website
Youth Force Declaration for Change
Youth Force Declaration for Change infographic 
Top 10 ideas
All young people have the right to sexual and reproductive health services that are accessible, available, safe, affordable, quality-approved, youth-friendly and adapted to their specific needs.

Meaningful youth participation at all levels of decision-making is crucial in the development of effective SRHR and HIV programmes; participation must include not only those with resources but also those on the ground levels.

We demand ACCESS to youth-friendly prevention, treatment, care and support services for all young people, including young people living with HIV, so that our right to the highest attainable standard of health may be achieved.

Comprehensive and appropriate information about HIV should be accessible to all young people including those with disabilities, in & out of schools, migrants & those living in geographically isolated and disadvantaged areas.

We demand increased funding for research that focuses on HIV among young people addressing not only prevalence rates but also lifestyles and behavioral patterns, risk factors and other areas needed for HIV response.

Increase ACCESS to financial & technical support that strengthens youth organizations and youth led initiatives to increase our impact in the HIV response, by creating mechanisms that assure money transfers down to the ground.

We demand universal access to sexual and reproductive health integrated services that includes the specific needs of women and girls, respecting their human rights and an emphasis on equity and respect for diversity.

Eliminate social, cultural and political barriers in accessing health services among young people by making interventions gender and age-responsive, rights-based, and sexual orientation and gender identity-inclusive.

We demand more support for capacity building programs that empower youth and enable them to participate effectively in policy making especially concerning areas that affect them like environment, health and rights.

We demand PROTECTION by the law. We must not be criminalized because of our sexual orientation and gender identity, drug use, HIV status, disability and/or sex work.

You can check out all the ideas and more information on the project site.

RC Watch vol 1, issue 2 // What RCs has Toronto seen the most of so far?

(Check out our previous introductory post on research chems for more background info.)
Here's a list of some of the trends we've seen to date in Toronto, but we're going to keep you posted on what we know is happening with Research chems locally.  If you have any questions about RCs that you'd like to know more about, or if you have noticed any emerging RC trends, please get in touch with us at or by approaching any of our volunteers.
MDPV (Methylenedioxypyrovalerone)
aka "super coke"
Despite the nickname, this substance is chemically unrelated to cocaine and produces significantly different effects: it is a (much) longer-term stimulant that is better compared to speed.  While the branding helped initial sales of this substance, many users who experimented with it based on liking cocaine found themselves experiencing negative effects (generally due to the length and strong emotional levels of the high).  MDPV is a common ingredient in “bath salts” formulations sold online and via head shops.  As with any stimulant, prolonged and repeated use can result in users staying up for days in a row, potentially impairing cognitive judgement and producing delusional and paranoid mental states, i.e. psychosis. 
MCAT (Mephedrone)
aka "max volume" (local), "meow meow" (UK)
Mephedrone was developed in the UK and distributed quite cheaply, quickly gaining popularity amongst youth at a time when more common drugs like E became increasingly scarce.  Use has declined as more and more negative side-effects are reported, including decreased sexual ability in males, apparently high abuse potential and (in the case of some heavier chronic users) health problems including vasoconstriction leading to vein collapse.  Media scare reports in the UK and underground anti-Mephedrone campaigns emerged as use spread, it became increasingly uncool to be known as a user of the drug, and laws were tightened.  Chemical manufacturing companies marketing RCs in the UK have since made a point of pricing their new substances (like MXE) much higher so as to avoid the same explosion of underage use and the negative media attention that was associated with it.
2C* (2C-B, 2C-I, 2C-E and related molecules, as well as 2C-T-2, 2C-T-7, etc)
While these substances have existed for decades, being first synthesized and described by Alexander Shulgin in PiHKAL in the 1970/80s, they have had much more limited distribution and use until quite recently.  Now these phenethylamine psychedelics have began appearing in place of MDMA/E and in some cases LSD (not on blotter, which isn't large enough to contain an active amount of these substances, but in small microdot pills).  This is despite the fact that the effects differ quite a bit from MDMA/MDA - these psychedelics tend to be longer-lasting, more hallucinogenic, less euphoric, less empathogenic, more physically uncomfortable, more anxiety-producing and more likely to produce introverted states in social situations.
Important to note is that the 2C*s are much more potent than MDMA, especially when snorted, and anyone who is used to snorting MDMA or E pills should be very cautious with new batches because of the chance of an unpleasantly strong psychedelic trip if they have actually been given 2C*s.
As well, the related but separate 2C-T-* group has a particular warning attached to it, as 2C-T-7 has been linked to accidental lethal overdoses in experimental users (even ones who knew exactly what they were consuming), especially in those users who have been snorting rather than eating the drugs. More information can be found at (this link is over a decade old, so doesn't discuss many of the newer RCs).
MXE (Methoxetamine)
MXE is a ketamine derivative that was developed in the UK in 2010 with the specific intent of being distributed on the "grey market" in place of K, which was facing stiffer and stiffer legal controls in many countries.  Although many users experimenting with MXE have sought it out based on the hope that it is similar to K, most users report the effects as being more comparable to opiates.
It has been advertised as being "bladder friendly" and was designed in an attempt to avoid the bladder damage issues that have been reported by heavy, chronic ketamine users.  Being sold in the wake of the UK's mephedrone wave, distribution was originally done at a higher price than necessary in order to limit the speed at which the substance spread.  Despite the initial promise of "a safer ketamine," overdose deaths have since been reported and lawmakers are quickly moving to enact bans on the substance.  Russia and Switzerland have banned MXE since late 2011, and the UK rushed through a temporary ban while they wait to get around to discussing a permanent ban.  In Canada, MXE may be considered illegal based on PCP analogue laws - updates on this as we learn them.
PMA/PMMA (para-Methoxyamphetamine/para-Methoxymethamphetamine)
Two related but different amphetamine-class drugs, PMA and PMMA have increasingly appeared in place of E/MDMA and (in the case of PMA) LSD.
PMA acts as a psychedelic without being particularly stimulating or euphoric.  PMMA, instead, acts primarily as a stimulant.  Both have been linked to numerous overdose deaths, including PMMA in early 2012 in Western Canadian provinces where it was sold as pressed "ecstasy" pills.
The dangers related to PMA/PMMA are for two different primary reasons.  In the case of PMA, the substance acts as a monoamine oxidase inhibitor (MAOI), a substance which increases the potency and toxicity of many other drugs and even certain foods.  When PMA and MDMA are taken together (just like when any MAOI and MDMA are taken together), the risk of serotonin syndrome can be increased.
PMMA, on the other hand, acts as a physical stimulant which can raise a user's blood pressure and heart rate.  These effects can occur at doses lower than the other psychoactive effects, and so users who think they are taking normal ecstasy will assume that their pill is just "weak"/"bunk" and increase their dose. The overdose threshold for PMMA is lower than for MDMA, and users can reach the point of a dangerous stimulant overdose before they realize that they have taken anything unusual. As this is a particular health concern in Canada right now, be extra cautious about E and MDMA - test your pills and never re-dose because something seems too weak (who wants to double up on something that's crap anyway, right??). If you feel really sick after dosing & none of the normal tricks work (take a break, drink some water or something with electrolites, use the washroom, lie down, etc.) think about heading to the ER. 
AMT (Alpha-Methyltryptamine)
AMT is a psychedelic stimulant of the tryptamine family that is not typically found in place of other drugs.  However, as it is often described as having a particularly unique set of effects, it has achieved a fair level of popularity on its own. While not extremely common, it is definitely more common than many other experimental psychedelics. First developed in the 1960s, it experienced a boost in popularity beginning in the '90s as commercial chemical supply distribution became more widespread. AMT currently remains legal in most countries, including Canada.
BZP (Benzylpiperazine)
A euphoric stimulant which has been marketed under "legal high"/"ecstasy alternative" brands, BZP is now banned in a handful of countries but remains legal in Canada. Although no deaths have been reported from BZP alone, deaths have been reported in people consuming BZP and MDMA together, however BZP could not be identified as a direct cause in those cases. Nonetheless, the list of negative side-effects is substantial:
[Patients with mild to moderate toxicity experienced symptoms such as insomnia, anxiety, nausea, vomiting, palpitations, dystonia, and urinary retention. Significantly, fourteen toxic seizures were recorded with two patients suffering life-threatening toxicity with status epilepticus and severe respiratory and metabolic acidosis. It was concluded that BZP appears to induce toxic seizures in neurologically normal subjects. The results of this study and others like it showed that BZP can cause unpredictable and serious toxicity in some individuals, but the data and dosage collection were reliant on self reporting by drug users, which may result in under-reporting, and there were complicating factors like the frequent presence of alcohol and other drugs.]
The above information came from a study in Christchurch, New Zealand: 

How are we supposed to go forward from here with the possibility that any street drug could contain something we haven't even heard of yet?
The same old approach still holds true in this new situation:
Know yourself, know your substance and know your source!
Knowing yourself: Recognize when the effects of something you've taken don't match what they should. Try to familiarize yourself with information aobut RCs that you could possibly encounter and know what effects to be looking out for.
Knowing your substance: TEST!!! If at all possible, test every batch with a testing kit. While testing kits used to only identify a small handful of major substances, there are now kits which can detect many dozens of different things, ranging from illegal drugs to unusual RCs to major pharmaceuticals.
Contact TRIP! for more information on testing, and also take a look at the TestKitPlusDanceSafe , EZ Test  and Bunk Police  websites. If you absolutely can't get something tested, you should still learn to be as skilled as possible at assessing your drugs by appearance, taste and other means (the common ketamine 'burn test' is a good example of another testing method).
Knowing your source: Part of this also means knowing that your source may be honest with you but still not realize that they were sold something weird. While most dealers won't be willing to tell you in-depth information about their own sources, you should try to get a sense of whether they have extremely reliable and consistent links or whether they switch suppliers and are kind of hit-or-miss every time they pick up.
Likewise, if you're getting RCs from a chemical supply company, realize that not all companies are the same - many of the less legitimate ones will sell impure products, poorly-made products, or even sell totally mislabelled products when they've run out.  Get as many reviews as you can, make sure that online reviews aren't just spam put out by the company, and try to get a sense of whether the company really distributes large amounts for research purposes or is just some random person in a basement somewhere. 
(Check out our previous introductory post on research chems for more background info.) 

Youth Pride BBQ Monday, June 25

fabric rainbow 

Empower, TRIP! and CTCHC/Shout are co-hosting a pride BBQ. Please join us for an afternoon of yummy food, sun, and some loud and proud tunes! The event is open to LGTBQ youth and allies, aged 16-29. There will be yummy food, a DJ, art making activities, performances, and more!

Details: Monday, June 25, 2012
Time: 2:00-4:00pm
Location: Central Toronto Community Health Centre/Shout

For youth familiar with our space, the event will be held on the third floor. There will be signs however, and lovely front desk staff to guide folks who may be new to the space. This is an LGTBQ safe space and accessable. Please contact us if you have accessability questions. 


Youth Pride BBQ -poster 

RC Watch vol 1, issue 1 // Why designer drugs are turning up in more places than your bath (salts)


 mephedrone bag

RCs – research chemicals, which are sometimes called designer drugs and are more properly described as unresearched chemicals, are becoming increasingly common, both in semi-legal grey areas like "bath salts" and "plant fertilizer" as well as in the underground illegal market.

TRIP! will be issuing this monthly bulletin regarding trends in research chems.  If you have any questions about specific RCs, or have been hearing about any new ones that seem to be appearing, feel free to send us an e-mail at or chat up one of our volunteers.


What exactly are RCs?


RCs are chemicals which have yet to be researched and/or have been created for research purposes but haven't gone through rigorous clinical study.  Because of this, anyone considering using research chems should do very thorough research first.   Make sure to look into effects, side-effects, dosages and known risks, even more so than with "familiar" drugs - which you should always be as knowledgeable as possible about anyway ;)

As well, it is extremely important that you understand that you are essentially acting as a guinea pig, and many of these substances may only seem safe until a hospitalization or fatality occurs "in the wild."  Even if there are no serious short-term side-effects, long-term problems could accumulate and remain undetectable for years.


from Erowid:

"Although some people are willing to ingest these chemicals for their effects, it is not reasonable to assume that these chemicals are in any way 'safe' to use recreationally.  Although all psychoactive use involves risk, this class of chemicals has undergone virtually no human or animal toxicity studies and there is little to no data on possible long term problems, addiction potential, allergic reactions, or acute overdoses."


When you contrast this with drugs like LSD, MDMA and even now K which have decades of formal research behind them, the unknown risk factor essentially becomes infinite.  However, nowadays you may be encountering these substances whether you seek them out or not, so it's important that you familiarize yourself with the world of RCs even if you don't intend to be consuming them.


This is because RCs - some of which were initially synthesized years ago - are popping up all over the place these days…


Where are they showing up?


While more and more people are acquiring RCs deliberately and selling them under their actual names, many RCs are also sold in place of already-popular drugs like MDMA/E, K, LSD and so on.  This is because there is already established demand in the black market for these substances, and so it can be much easier to move a bag of methoxetamine by calling it "K" or PMMA by calling it "E" than by trying to explain what they actually are to reluctant customers.


Why are they now showing up more and more?


Technology and globalization is one reason. Although a flip through PiHKAL and TiHKAL will reveal more decades-old psychedelics than you'll be able to keep track of, there are now more chemical companies producing them in high quantities, and it is easier for these suppliers to take orders online & ship products worldwide.


Prohibition is the other big reason.  Recent years have seen repeated tightening of laws regarding possession, distribution and production of common street drugs like MDMA, K, and LSD.

Even though it now seems to be more likely for a user to experience a toxic overdose from PMMA than from MDMA, it is a much more serious crime to be found with a shipment of MDMA, actually encouraging the distribution of a more dangerous substance.  Likewise, it is far safer to get caught with MXE than with K, even though MXE has been associated with recent lethal overdoses and K is still respected as a mostly-safe pharmaceutical anaesthetic.

It's likely that the more prohibition is expanded, the greater the number of unresearched substances we will see on the black/grey market.  While governments are attempting to push anti-analogue laws (essentially, very broad laws which try to make it illegal to choose to alter your consciousness in any way) and other measures which would ban RCs outright, technology continues to provide people with ever-expanding ways to get around the law, and prohibition measures simply can't help but fall further and further behind. 


Tech blog Gizmodo just posted a writeup on this topic:

From that post: "If you want any evidence that drugs have won the drug war, you just need to read the scientific studies on legal highs," -- Vaughan Bell, MindHacks


What RCs has Toronto seen the most of so far?










(For more info on these, see post #2 .) 


Some of these drugs fit the RC/designer drug qualification of being deliberate attempts to circumvent laws and create legal highs, others are simply largely-unknown chemicals that have existed under the radar for some time and are increasingly showing up in place of more common ones (such is the case when blotter acid turns out to be DOI or DOB instead of LSD).


In coming posts, we'll explore these substances in more depth.  If you have any questions about RCs that you'd like to know more about, or if you have noticed any emerging RC trends, please get in touch with us at or by approaching any of our volunteers.

For now, if you need research-based information immediately on a specific substance, consult Erowid.


Toronto Youth Drug Survey

Research Chemicals and Pill Testing

Over the last month there have been a number of deaths and hospitalizations in Canada due to adulterated MDMA with PMMA, an analog derived from anise oil.  It's really important to test your supply in order to avoid bunk pills. Many users who take these adulterated pills don't feel them kick in and end up redosing, thus experiencing overdoses.  If you do take a pill and you don't feel it hit soon enough, avoid redosing as it could potentially be PMMA.  These deaths did occur in Western Canada, and while we haven't heard anything around PMMA in Toronto, there are similar concerns about bunk pills on the eastern front. This is just another example of what happens when you crack down on precursers (like safrole oil), as underground chemists will look for other new ways to synthesize legal analogs, which can be more dangerous than the illegal drugs they are based on.  While the B.C. police will not release the identity of the pills that caused these deaths, we encourage the community to do their own research and share information online.

Recently, a strange brown powder has resulted in a number of hospitalizations in Owen Sound.  One of our harm reduction service users also had a strong reaction to a similar strange brown powder, and we were able to lend them a testing kit.  The pills tested positive for what might be 5-MeO-DMT, as well as speed.  While there are lots of great posts online about using the DanceSafe Testing kits, it's hard to come across information around the newer research chemicals.  Some research chemicals like piperazines or PMMA which are a very common adulterant do not produce any colour changes depending on the reagent. The Mandelin EZ testing kit does screen for PMMA, so that is probably your best bet for catching this substance.

Others can produce colours that look similar to other drugs, so it's really important to do all of the tests (Mecke, Marquis, Simons Reagant, Mandelin, etc.) to know what is in your pill.  As such, we've take the liberty of sharing some newer research done by the online community of international drug nerds.  Please use the images below to help further determine what adulterants may be lurking in your pill.  Feel free to email us at if you would like to purchase a testing kit in Canada. The following chart shows some of the range of research chemicals that are showing up on the scene, and below are the Mecke, Marquis, Mandelin and Simons Reagant results for some of these chemicals.

 Emerging Research Chemicals


Marquis – yellow, changing to light green, and then fading over
Mecke – yellow/brown/green, green fades over time
Mandellin -

Marquis – yellow, changing to green, and then
fading over time
Mecke – yellow/brown
Mandellin – yellow fading to

Marquis – Green-blue with yellow edges, fades to
blue, fades over time
Mecke – dark brown, very fast
Mandellin -

Marquis – Very faint brown, fading to clear.

Mecke – Yellow-brown fading to reddish brown
Mandellin – Yellow w/tinge
of green fades to clear over time

Marquis – Very faint
brown, fading to clear.
Mecke – Dark brown
Mandellin – Yellow w/tinge of
green fades to clear over time

Marquis – Very faint
brown, fading to clear.
Mecke – Yellow-brown fading to Rusty
Mandellin – Yellow w/tinge of green fades to clear over time

Marquis – Almost no reaction, slight brown.

Mecke – Black/dark purple fading to orangy-red
Mandellin – Orange fading
to clear over time

Marquis – Almost no reaction,
slight brown.
Mecke – Black/dark purple fading to
Mandellin – Orange fading to clear over

Marquis – Almost no reaction, slight brown.

Mecke – Black/dark purple, fading slowly if at all.
Mandellin – Orange
fading to clear over time


Beta Ketones and Various RC stimsempathogens

Beta Ketones and Various RCs

Marquis – yellow
Mecke – no reaction (kept the brownish
color it had out of bottle)
Mandellin – Clear
Robadope -
Simons – Negative

Mephedrone, Buphedrone, Ethcathinone, 3
and 4 Flouromethcathinone
Marquis – no reaction
Mecke – slight
brown, almost no change.
Mandellin – slight browning.
Robadope -
Simons – Positive

MDPV, MDPPP, Methylone, Butylone:

Marquis – yellow
Mecke – red-brown
Mandellin – clear
Robadope -
Simons – MDPPP/MDPV Negative, Methylone/Butylone

Methedrone (DANGER! BAD STUFF!)
Marquis -
Mecke – orange
Mandellin – orange
Robadope -
Simons – Positive


All I know for sure on test results is Robadope should be
positive, and Simons negative.

Marquis -
Mecke – Red
Mandellin – yellow
Robadope -
Simons – Negative
NOTE: Previous 5-IAI results posted were for
FAKE PRODUCT. The old, inaccurate results have been removed.

Marquis – no reaction if only
small amount used. If you dump a whole pile of it in, it’ll turn brownish orange.
Mecke – no reaction
Mandellin – no reaction
Robadope -
Simons – Negative

All slow and weak color changes.
Marquis -
Mecke – brown
Mandellin – yellow/brown
Robadope -
Simons – Negative

Marquis – Light brown to
very dark brown depending on trace impurities.
Mecke – Dark
Mandellin – Dark Brown
Robadope – Positive
Simons -

Marquis – no reaction
Mecke -
Mandellin – light blue
Robadope – Positive
Simons -

Sample from BOLT brand single constituant
ephedrine pills.
Marquis – no reaction
Mecke – no reaction
Mandellin -
Robadope – Negative
Simons – Positive

(anhydrous, USP)

Marquis – no reaction
Mecke – slight
Mandellin – no change
Robadope – Positive
Simons -

Marquis – no reaction
Mecke – slight
Mandellin – no change
Robadope – Negative
Simons – Positive?
It should be positive…

Not shown.
All reactions slow. Strange colors, changing over time, all colors weak.
Robadope -
Simons – Negative


JWH-018, JWH-073, JWH-081
Marquis – Yellow quickly changing to brown

Mecke – Brown/Yellow
Mandellin – Dark

Marquis – Yellow/orange
Mecke -
Mandellin – Dark red-brown

Marquis – Red,
fading to orange over time
Mecke – Orange
Mandellin – Dark

Marquis – Brown/yellow, hints of green

Mecke – grey/brown
Mandellin – Dark

Marquis – Red/orange
Mecke – Blue,
fading over time.
Mandellin – Brown

Marquis -
Mecke – Blue-green, fading over time
Mandellin -




 Borrowed from the friendly international drug nerd community!  Thanks everyone for documenting these results. 


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